The Cerebrovascular Disease and Stroke Center at the UC Neuroscience Institute is committed to advancing treatments that offer the best possible outcomes for patients. Our team is involved in research from the basic science level to clinical trials. A list of current studies appears below. For more information, please click on the link to contact the coordinator.

Surgical/Endovascular Clincial Trials

The following link is a PDF (Adobe Reader) file summary of the UC Cerebrovascular Disease and Stroke Center clinical trials.
Neurovascular Program Clinical Trials and Interventional Protocols - November 2009 »

Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE)
Funded by: NINDS/National Institutes of Health/UCLA
Principal Investigator: Thomas Tomsick, MD
Janice Carrozzella, RN, at (513) 558-4789 or 

Carotid Occlusion Surgery Study (COSS)
Funded by: National Institutes of Health/University of North Carolina 
Principal Investigators: Mario Zuccarello, MD, and Matthew Flaherty, MD
Contact: Carolyn Koenig, RN, at (513) 558-3518 or 

Interventional Management of Stroke Study (IMS III)
Funded by: NINDS/National Institutes of Health
Principal Investigators: Joseph Broderick, MD, and Thomas Tomsick, MD
Contact: Joyce Zeigler at (513) 558-3628 or 
Contact: Judith Spilker, RN, at (513) 558-5430 or
Contact: Janice Carrozzella, RN, at (513) 475-8793 or 

Stenting vs. Aggressive Medical Management for Preventing Recurrent Events in Intracranial Stenosis (SAMMPRIS)
Funded by: NINDS/ National Institutes of Health/Medical University of South Carolina 
Principal Investigators: Andrew Ringer, MD, and Pooja Khatri, MD
Contact: Carolyn Koenig, RN, or 

Stroke/Medical Clinical Trials

Hemorrhagic and Ischemic Strokes Among Blacks and Whites
Funded by: NINDS/National Institutes of Health
Principal Investigators: Brett Kissela, MD, and Dawn Kleindorfer, MD
Contact: Kathleen Alwell, RN, at (513) 558-1126 or 

Siblings with Ischemic Stroke Study (SWISS)
Funded by: NINDS/National Institutes of Health/Mayo Clinic
Principal Investigator: Brett Kissela, MD
Contact: Kathleen Alwell, RN, at (513) 558-1126 or 

Genetic and Environmental Risk Factors of Hemorrhagic Stroke (GERFHS) Coordinating Center 
Funded by: NINDS/National Institutes of Health
Principal Investigator: Daniel Woo, MD
Contact: Mary Haverbusch, RN, at (513) 558-3992 or 

Familial Intracranial Aneurysm (FIA) Coordinating Center
Funded by: NINDS/National Institutes of Health
Principal Investigator: Joseph Broderick, MD
Contact: Laura Sauerbeck, RN, at (513) 558-1742 or 

A Grant Under the NINDS' Specialized Programs of Translational Research in Acute Stroke (SPOTRIAS) Program
Funded by: NINDS/National Institutes of Health
Principal Investigator: Joseph Broderick, MD
Contact: Traci Doellman, RN, at (513) 558-5359 or

The Combination Approach to Lysis Utilizing Eptifibatide and rt-PA-Enhanced Regiment (CLEAR-ER Study) Coordinating Center
Funded by NINDS/National Institutes of Health
Principal Investigator: Arthur Pancioli, MD
Contact: Pamela Schmit, RN, at (513) 558-6142 or

The Spot Sign for Predicting and Treating Intracerebral Hemorrhage Growth (STOP-IT) Coordinating Center
Funded by: NINDS/National Institutes of Health
Principal Investigator: Matthew Flaherty, MD
Contact: Janice Carrozzella, RN, at (513) 558-4789 or 

Albumin in Acute Ischemic Stroke (ALIAS)
Funded by: National Institutes of Health/University of Miami
Principal Investigator: Pooja Khatri, MD
Contact: Irene Ewing, RN, at (513) 558-2430 or

Insulin Resistance Intervention after Stroke (IRIS) Trial
Funded by: NINDS/National Institutes of Health/Yale University
Site Principal Investigator: Dawn Kleindorfer, MD
Contact: Jennifer Osborne, RN, at (513) 558-4241 or 

fMRI of Language Recovery Following Stroke in Adults
Funded by: NINDS/National Institutes of Health
Principal Investigator: Jerzy Szaflarski, MD, PhD
Contact: Christi Banks, CCRP, at (513) 558-3975 or

fMRI of Language REcovery Following STroke in Adults -- Extension Study
Funded by: NINDS/National Institutes of Health
Principal Investigator: Jerzy Szaflarski, MD, PhD
Contact: Christi Banks, CCRP, at (513) 558-3975 or

The Effects of Repetitive Transcranial Magnetic Stimulation on Post-Stroke Aphasia
Funded by: University Research Council at UC
Principal Investigator: Jerzy Szaflarski, MD, PhD
Contact: Christi Banks, CCRP, at (513) 558-3975 or

Cerebrovascular Fellowship Training Program
Funded by: NINDS/ National Institutes of Health
Dates: 7/1/2006 to 6/30/2011
Principal Investigator: Joseph Broderick, MD
Contact: Dawn Kleindorfer, MD, at (513) 558-5328 or

The Significance of Intracranial Hemorrhage after Revascularization Therapy
Funded by NINDS/National Institutes of Health
Dates: 7/1/2007 to 1/31/2012
Principal Investigator: Pooja Khatri, MD
Contact: Pooja Khatri, MD, at (513) 558-6411 or

Etiology of Geographic and Racial Differences in Stroke (REGARDS)
Funded by: NINDS/University of Alabama Birmingham
Dates: 4/1/2008 to 11/30/2012
Principal Investigator: Brett Kissela, MD
Contact: Brett Kissela, MD, at (513) 558-5445 or

The Effect of Improved Hospital Reimbursement for rt-PA Use in Ohio
Funded by: the Association of American Medical Colleges/Centers for Disease Control and Research
Dates 10/1/2006 to 9/30/2010
Principal Investigator: Dawn Kleindorfer, MD
Contact: Dawn Kleindorfer, MD, at (513) 558-5328 or

Effect of Socieoeconomic Status on Outcome after Stroke
Funded by: NINDS/National Institutes of Health
Dates 2/15/2006 to 1/31/2011
Principal Investigator: Dawn Kleindorfer, MD
Contact: Kathy Alwell, RN, at (513) 558-1126 or