Cerebrovascular Center

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Research Yields New Insight Into Gene Mutations Linked to Brain Bleeds

Friday, February 3, 2012
Keith Herrell
(513) 558-4559

CINCINNATI—An innovative approach to genome screening has yielded clues about rare mutations that may render people susceptible to brain bleeds, according to research led by a University of Cincinnati (UC) neurologist.

Joseph Broderick, MD, Albert Barnes Voorheis Chair of Neurology at the UC College of Medicine and research director of the UC Neuroscience Institute, is presenting the research Friday, Feb. 3, at the American Stroke Association’s International Stroke Conference 2012 in New Orleans.

For the first time, scientists applied a process called whole exome sequencing to seek gene mutations in families in which multiple relatives have intracranial aneurysms—weakened, ballooned-out areas in arteries of the brain that can rupture and cause a stroke, resulting in bleeding within the brain.

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